BiochemistryScientific ReportsPeer-reviewed
Gliflozins, sucrose and flavonoids are allosteric activators of lecithin:cholesterol acyltransferase
Akseli Niemelä, Laura Giorgi, Sirine Nouri…·Artturi Koivuniemi
The paper identifies gliflozins, sucrose, and flavonoids as activators of LCAT using in silico predictions and in vitro assays, highlighting their potential in treating LCAT deficiency and atherosclerosis.
5 citations