Author

Laura Giorgi

University of HelsinkiORCID 0009-0001-1425-4904Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Akseli NiemeläiD· 2 shared Artturi KoivuniemiiD· 2 shared Sirine NouriiD· 2 shared Betül YurttaşiD· 1 shared Juho HeinineniD· 1 shared Khalfa Benadouda· 1 shared Khushbu RauniyariD· 1 shared Michael JeltschiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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2 shared papersPharmacology & Toxicology

Akseli NiemeläORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintAug 13, 2025

Modifications of the 22A apoA-I mimetic peptide sequence improve the anti-atherosclerotic properties of synthetic HDL

Sirine Nouri, Laura Giorgi, Akseli Niemelä…·Artturi Koivuniemi

This study modifies the 22A apoA-I mimetic peptide sequence to enhance cholesterol efflux and LCAT activity in synthetic HDL, without affecting plasma HDL remodeling.

1 citation

humanproteomics

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BiochemistryScientific ReportsPeer-reviewedOct 30, 2024

Gliflozins, sucrose and flavonoids are allosteric activators of lecithin:cholesterol acyltransferase

Akseli Niemelä, Laura Giorgi, Sirine Nouri…·Artturi Koivuniemi

The paper identifies gliflozins, sucrose, and flavonoids as activators of LCAT using in silico predictions and in vitro assays, highlighting their potential in treating LCAT deficiency and atherosclerosis.

5 citations

humanproteomics

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