Author

Jörg S. Hartig

University of KonstanzORCID 0000-0001-6601-7217Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Benjamin RiesiD· 1 shared Dirk Gottschling· 1 shared Franziskus HauthiD· 1 shared Gary E. Aspnes· 1 shared Gisela SchnappiD· 1 shared Holger KleiniD· 1 shared Jennifer R. FlemingiD· 1 shared Maike SpöringiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Benjamin RiesORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Structural Biology XPeer-reviewedJun 18, 2025

Indel-driven evolution of the canavanine tRNA-editing deacetylase enzyme CtdA

Nino Tabagari, Franziskus Hauth, Jennifer R. Fleming…·Olga M. Mayans

This study identifies CtdA, a tRNA deacetylase that removes canavanine from mischarged tRNAArg, and reveals its structural and evolutionary relationships to B3/B4 domains.

2 citations

bacteria (other)structural biology

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintJan 21, 2025

Small molecule-controlled gene expression: Design of drug-like high affinity small molecule modulators of a custom-made riboswitch

Vera Hedwig, Maike Spöring, Gary E. Aspnes…·Oliver Hucke

The paper designs a drug-like small molecule modulator of a custom riboswitch, achieving high affinity and orthogonality for gene expression control in human cells.

DOI 10.1101/2025.01.21.634073

humanexperimental assay

𝕏 PostBluesky