Mathilda T.M. Mommersteeg

This study identifies the Slit2-Robo1 pathway as critical for cardiac sympathetic innervation during development, showing reduced innervation in Slit2-/- and Robo1-/- mice.

This study shows that circadian rhythms in glycolysis and cell cycle progression are essential for cardiomyocyte proliferation and heart regeneration in zebrafish.

The paper identifies prolonged innate and adaptive immune responses as critical for heart regeneration in surface fish, showing that inhibiting these responses impairs regeneration.

The paper identifies transient Runx1-expressing endocardial cells in injured zebrafish hearts that transition towards myofibroblast or haemogenic endocardium identities.

The paper presents a chromosome-level genome of surface fish Astyanax mexicanus and uses it to identify genetic factors contributing to trait evolution in cavefish populations.

This study shows that Runx1 inhibits heart regeneration in zebrafish by promoting scar formation and reducing myocardial proliferation and survival.