Zhilian Hu

Absence of a prolonged macrophage and B cell response inhibits heart regeneration in the Mexican cavefish

The paper identifies prolonged innate and adaptive immune responses as critical for heart regeneration in surface fish, showing that inhibiting these responses impairs regeneration.

Injured endocardium obtains characteristics of haemogenic endothelium during adult zebrafish heart regeneration

The paper identifies transient Runx1-expressing endocardial cells in injured zebrafish hearts that transition towards myofibroblast or haemogenic endocardium identities.

A chromosome level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution.

The paper presents a chromosome-level genome of surface fish Astyanax mexicanus and uses it to identify genetic factors contributing to trait evolution in cavefish populations.

Disruption of the kringle 1 domain of prothrombin leads to late onset mortality in zebrafish

This study shows that disrupting the kringle 1 domain of prothrombin in zebrafish causes late-onset mortality due to impaired clot formation, revealing its role in thrombin biosynthesis and activation.