Author

Ian Curtin

University of North Carolina at Chapel HillORCID 0000-0001-6650-7574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jason L. SteiniD· 4 shared Felix A. KyereiD· 3 shared Carolyn M. McCormick· 2 shared David BorlandiD· 2 shared Guorong Wu AiD· 2 shared Hong YiiD· 2 shared Karen HuangiD· 2 shared Liam T. Davis· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Jason L. SteinORCID

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4 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 11, 2026

From Abandoned Scripts to FAIR Community Pipelines: Rescuing Orphan Bioinformatics Workflows with nf-core - Lessons from Light-Sheet Fluorescence Microscopy

Carolin Schwitalla, Luis Kuhn Cuellar, Matthias Hörtenhuber…·Sven Nahnsen

The paper re-engineers an abandoned MATLAB-based image analysis toolkit into a sustainable, FAIR-compliant Nextflow workflow for light-sheet microscopy.

DOI 10.64898/2026.07.29.741447

imagingexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 22, 2026

Chd8 haploinsufficiency leads to molecular layer heterotopias and age-dependent cortical expansion

Felix A. Kyere, Ian Curtin, Ziquan Wei…·Jason L. Stein

This study identifies molecular layer heterotopias and age-dependent cortical expansion in Chd8 haploinsufficient mice, linking them to neuronal migration defects and autism-related brain overgrowth.

3 citations

mouseimaging

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 19, 2026

CellPheno: A High-throughput Computational Platform for Quantifying Cellular Resolution Whole Brain Microscopy Images

Ziquan Wei, Ian Curtin, Felix A. Kyere…·Guorong Wu A

CellPheno is a 3D nuclei segmentation tool for whole-brain microscopy that enables efficient morphometry and co-localization analysis across multiple cell types in mouse brains.

DOI 10.64898/2026.03.17.712391

mouseimaging

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 7, 2025

Early cell cycle genes in cortical organoid progenitors predict interindividual variability in infant brain growth trajectories

Madison R. Glass, Nana Matoba, Alvaro A. Beltran…·the Infant Brain Imaging Study Network

The paper links early cell cycle gene expression in cortical organoids to interindividual variability in infant brain growth trajectories.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky