Felix A. Kyere

The paper re-engineers an abandoned MATLAB-based image analysis toolkit into a sustainable, FAIR-compliant Nextflow workflow for light-sheet microscopy.

This study identifies molecular layer heterotopias and age-dependent cortical expansion in Chd8 haploinsufficient mice, linking them to neuronal migration defects and autism-related brain overgrowth.

CellPheno is a 3D nuclei segmentation tool for whole-brain microscopy that enables efficient morphometry and co-localization analysis across multiple cell types in mouse brains.

The paper identifies cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation and links these to regulatory mechanisms of neuropsychiatric disorder risk variants.