Author

Juan M. Lozano Gil

Instituto de Salud Carlos IIIORCID 0000-0002-0422-9887Unclaimed ORCID profile · follow to get notified of new preprints

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Approach:experimental assay· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Diana García‐MorenoiD· 2 shared Sylwia D. TyrkalskaiD· 2 shared Víctoriano MuleroiD· 2 shared Alicia Martínez‐LópeziD· 1 shared Andrés JereziD· 1 shared Annamaria PedotoiD· 1 shared Cristina BeléndeziD· 1 shared Cristina Díaz de HerediaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Diana García‐MorenoORCID

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2 papers

Recent·Most cited

Inhibition of NLRP1 Inflammasome Activation by Tyrosine Kinase Inhibitors Restores Erythropoiesis in Diamond-Blackfan Anemia Syndrome

Juan M. Lozano Gil, Lola Rodríguez‐Ruiz, Manuel Palacios, Jorge Peral, Susana Navarro, José Luís Fuster, Cristina Beléndez, Andrés Jerez, Laura Murillo, Cristina Díaz de Heredia, Guzmán López-de-Hontanar, Josune Zubicaray, Julián Sevilla, Francisca Ferrer‐Marín, María P. Sepulcre, , Víctoriano Mulero

This study shows that tyrosine kinase inhibitors can restore erythropoiesis in Diamond-Blackfan Anemia by inhibiting NLRP1 inflammasome activation.

bioRxiv · Feb 20, 2025 · PreprintImmunology

Macrophage Inflammasome Activation Drives Anti-inflammatory Responses via Neutrophil-Derived ASC Speck Transfer and Gasdermin-Dependent Caspase-1 Inhibition

Annamaria Pedoto, Juan M. Lozano Gil, Mai Nguyen Chi, Georges Lutfalla, Diana García‐Moreno, María Luisa Cayuela, Sylwia D. Tyrkalska, Víctoriano Mulero

This study shows macrophage inflammasomes drive anti-inflammatory responses by transferring neutrophil-derived ASC specks and inhibiting caspase-1 via Gasdermin E.

bioRxiv · Jan 22, 2025 · PreprintImmunology