Synthetic BiologyJournal of Biological EngineeringPeer-reviewed
Termination sequence between an inducible promoter and ubiquitous chromatin opening element (UCOE) reduces gene expression leakage and silencing
Tomoki Yanagi, Shean Fu Phen, Jonah Ayala…·David M. Truong
The paper investigates how spacer sequences between a promoter and A2UCOE affect gene expression leakage and silencing in iPSCs, finding that an AT-rich poly-A terminator reduces leakage and enhances anti-silencing.
7 citations