Author
New York UniversityORCID 0000-0003-1808-2932Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Serena Generoso, Sarah Levovitz, Susanna Jaramillo…·David M. Truong
REWRITE enables scar-minimized rewriting of native human loci exceeding 100 kb in hPSCs, demonstrated through synthetic refactoring of the class-I HLA region.
Tomoki Yanagi, Shean Fu Phen, Jonah Ayala…·David M. Truong
The paper investigates how spacer sequences between a promoter and A2UCOE affect gene expression leakage and silencing in iPSCs, finding that an AT-rich poly-A terminator reduces leakage and enhances anti-silencing.
Tomoki Yanagi, Hiroaki Kikuchi, Koh Takeuchi…·Eisei Sohara
This study identifies ULK1-dependent AMPK activation mechanisms and shows MK8722 improves renal function in CKD.