Author

Laura Atkinson

Great Ormond Street HospitalORCID 0000-0001-6724-9589Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:metagenomics· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Judith BreueriD· 3 shared Julianne Rose BrowniD· 3 shared Nathaniel StoreyiD· 3 shared Sofia MorfopoulouiD· 3 shared Angelika Kopec· 2 shared Cristina VenturiniiD· 2 shared Oscar Enrique Torres MontaguthiD· 2 shared Sarah BuddleiD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Judith BreuerORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJan 13, 2025

Contaminating manufacturing plasmids and disrupted vector genomes present in liver tissue following adeno-associated virus gene therapy

Sarah Buddle, Li‐An K. Brown, Sofia Morfopoulou…·Judith Breuer

The paper identifies manufacturing plasmid sequences and disrupted vector genomes in liver tissue from a patient with AAV gene therapy-related hepatitis.

DOI 10.1101/2025.01.13.25320105

humanmetagenomics

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Genetic & Genomic MedicineGenome MedicinePeer-reviewedSep 9, 2024

Evaluating metagenomics and targeted approaches for diagnosis and surveillance of viruses

Sarah Buddle, Leysa Forrest, Naomi Akinsuyi…·Oscar Enrique Torres Montaguth

This study compares metagenomics and targeted approaches for virus detection, finding that targeted methods improve sensitivity while untargeted ONT offers better specificity.

66 citationstop 1%

humanmetagenomics

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Genetic & Genomic MedicineJournal of InfectionPeer-reviewedAug 7, 2023

Translating metagenomics into clinical practice of complex paediatric neurological presentations

Justin Penner, Jane K. Hassell, Julianne Rose Brown…·Sofia Morfopoulou

This study demonstrates that clinical metagenomics improves diagnostic outcomes for undiagnosed complex paediatric neurological cases, particularly in immunocompromised patients.

19 citations

humanmetagenomics

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