Author

Angelika Kopec

Great Ormond Street Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:metagenomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Judith BreueriD· 3 shared Julianne Rose BrowniD· 2 shared Laura AtkinsoniD· 2 shared Nathaniel StoreyiD· 2 shared Sofia MorfopoulouiD· 2 shared Alasdair BamfordiD· 1 shared Alexander LennoniD· 1 shared Amy I. Jacobs· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Judith BreuerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Antiviral drug synergy and mutational signatures in different epithelial cell models of RSV and hPIV infection

Samuel Ellis, Amy I. Jacobs, Shengyuan Zhang, Laura Buggiotti, Maximillian N. J. Woodall, Jila Ajeian, Helena J. Tutill, Charles M. Miller, Macheala Palor, Angelika Kopec, Elizabeth K. Haughey, Hongxia Ma, Mia Tomlinson, Rachel J. Williams, Christopher O’Callaghan, , Judith Breuer

This study evaluates antiviral drug synergy and mutational signatures of RdRp inhibitors against RSV and hPIV in epithelial cell models and primary airway cultures.

bioRxiv · Jan 13, 2026 · PreprintMicrobiology

Contaminating manufacturing plasmids and disrupted vector genomes present in liver tissue following adeno-associated virus gene therapy

Sarah Buddle, Li‐An K. Brown, Sofia Morfopoulou, Oscar Enrique Torres Montaguth, Mariacristina Scoto, Vanessa Herder, Anil Kumar Dhawan, Julianne Rose Brown, Laura Atkinson, Angelika Kopec, Dee Davis, Nathaniel Storey, Luis Campos, Neil James Sebire, Hannah L. Macpherson, , Judith Breuer

The paper identifies manufacturing plasmid sequences and disrupted vector genomes in liver tissue from a patient with AAV gene therapy-related hepatitis.

medRxiv · Jan 13, 2025 · PreprintGenetic & Genomic Medicine

Translating metagenomics into clinical practice of complex paediatric neurological presentations

Justin Penner, Jane K. Hassell, Julianne Rose Brown, Kshitij Mankad, Nathaniel Storey, Laura Atkinson, Nisha Ranganathan, Alexander Lennon, Jack C. D. Lee, Dimitrios Champsas, Angelika Kopec, Divya Shah, Cristina Venturini, Garth L. J. Dixon, Surjo Kiran De, , Sofia Morfopoulou

This study demonstrates that clinical metagenomics improves diagnostic outcomes for undiagnosed complex paediatric neurological cases, particularly in immunocompromised patients.

Journal of Infection · Aug 7, 2023Peer-reviewedGenetic & Genomic Medicine