Antonio Jose Costa-Filho

This study introduces ExVivo PhaseScan to generate high-resolution phase diagrams of physiological protein condensates and reveals how FUS mutations cause liquid-to-solid transitions in stress granules and nucleoli.

This study investigates the interaction of myristoylated GRASP65 and GRASP55 with lipid membranes using reconstitution and various analytical techniques, revealing their impact on membrane dynamics.

This study investigates how N-terminal acetylation affects biomolecular condensation using Grh1 in yeast, showing it alters condensate properties like size, stability, and structure.

This study shows phosphorylation of Grb2 drives phase separation, forming scaffolds that recruit and sequester wild-type dimers, redefining Grb2's role in signaling.