Author

Alexander N. Gorelick

Harvard UniversityORCID 0000-0001-6736-8246Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

A. Ari HakimiiD· 1 shared Barry S. TayloriD· 1 shared David M. CheekiD· 1 shared Dejan JuriciD· 1 shared Djamila BoermaiD· 1 shared Ed ReznikiD· 1 shared Emma C. E. WassenaariD· 1 shared Emma V. WatsoniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

A. Ari HakimiORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 25, 2024

A unique interplay of access and selection shapes peritoneal metastasis evolution in colorectal cancer

Emma C. E. Wassenaar, Alexander N. Gorelick, Wei-Ting Hung…·Kamila Naxerova

This study examines the evolutionary dynamics of peritoneal metastases in colorectal cancer, finding they are more heterogeneous than liver metastases but less diverse than locoregional metastases.

3 citations

humanstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintAug 18, 2020

Respiratory complex and tissue lineage drive mutational patterns in the tumor mitochondrial genome

Alexander N. Gorelick, Minsoo Kim, Walid Khaled Chatila…·Ed Reznik

The paper shows that mtDNA mutations in tumors are shaped by OXPHOS complexes, with specific mutational patterns in Complex I and V, and links these to improved survival in colorectal cancer.

1 citation

humanwhole-exome sequencing

𝕏 PostBluesky