Author
German Cancer Research CenterORCID 0000-0001-6754-4190Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Martha Julia Carreño-Gonzalez, Kimberley M. Hanssen, Ahmed Sadik…·Thomas G. P. Grünewald
This study shows that reduced EWSR1::ETS activity in Ewing sarcoma promotes immune evasion via the tryptophan-kynurenine-AHR axis, leading to worse clinical outcomes and tumor progression.
A. Katharina Ceranski, Martha Julia Carreño-Gonzalez, Anna C. Ehlers…·Thomas G. P. Grünewald
This study improves Ewing sarcoma cell culture conditions to better reflect physiological states, revealing metabolic gene signatures linked to oncogenic fusion proteins.
Jia Xiang Jin, Fabia Fuchslocher, Martha Julia Carreño-Gonzalez…·Thomas G. P. Grünewald
This study investigates how SMARCB1 loss in Epithelioid Sarcoma rewires epigenetic regulation, revealing therapeutic vulnerabilities through functional multi-omics analysis.
Endrit Vinca, Anna C. Ehlers, Alina S. Ritter…·Shunya Ohmura
This study identifies GLRX3 as a vulnerability in Ewing sarcoma driven by EWSR1::FLI1 fusion oncoproteins, showing its role in oxidative stress and iron homeostasis and potential therapeutic targeting.