Author
German Cancer Research CenterORCID 0000-0003-2718-9002Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Luuk A. Broeils, Jill Pilet, Maria K. Koshkina…·Sebastiaan van Heesch
The paper shows EWSR1::FLI1 fusion drives the production of cancer-specific neoproteins in Ewing sarcoma, revealing a reversible dark proteome with therapeutic potential.
Joaquín Olmedo-Pelayo, Laura Lobo-Selma, Daniel Delgado‐Bellido…·Enrique de Álava
This study identifies EXO1 as essential for Ewing sarcoma cell survival and shows its role in preventing genome instability and cell death by facilitating MiDAS.
Martha Julia Carreño-Gonzalez, Kimberley M. Hanssen, Ahmed Sadik…·Thomas G. P. Grünewald
This study shows that reduced EWSR1::ETS activity in Ewing sarcoma promotes immune evasion via the tryptophan-kynurenine-AHR axis, leading to worse clinical outcomes and tumor progression.
A. Katharina Ceranski, Martha Julia Carreño-Gonzalez, Anna C. Ehlers…·Thomas G. P. Grünewald
This study improves Ewing sarcoma cell culture conditions to better reflect physiological states, revealing metabolic gene signatures linked to oncogenic fusion proteins.
Jia Xiang Jin, Fabia Fuchslocher, Martha Julia Carreño-Gonzalez…·Thomas G. P. Grünewald
This study investigates how SMARCB1 loss in Epithelioid Sarcoma rewires epigenetic regulation, revealing therapeutic vulnerabilities through functional multi-omics analysis.