Author

Or Szekely

Duke UniversityORCID 0000-0002-9502-9337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Hashim M. Al‐HashimiiD· 2 shared Serafima GusevaiD· 2 shared Ainan GengiD· 1 shared Akanksha ManghraniiD· 1 shared Atul Kaushik RangaduraiiD· 1 shared Bei LiuiD· 1 shared Kai Smith· 1 shared Linshu Li· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Hashim M. Al‐HashimiORCID

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2 papers

Recent·Most cited

An A-T Hoogsteen base pair in a naked DNA hairpin motif: A Protein-Recognized Conformation

Serafima Guseva, Or Szekely, Ainan Geng, Kai Smith, Supriya Pratihar, Yeongjoon Lee, Linshu Li, Sophie Marianne Korn, Stephanie Gu, Hashim M. Al‐Hashimi

The paper shows that an A-T Hoogsteen base pair forms in naked DNA hairpins without protein binding, and identifies a DNA-specific motif stabilized by this pairing.

Angewandte Chemie International Edition · Apr 11, 2025Peer-reviewedBiochemistry

Quantitative and systematic NMR measurements of sequence-dependent A-T Hoogsteen dynamics uncovers unique conformational specificity in the DNA double helix

Akanksha Manghrani, Atul Kaushik Rangadurai, Or Szekely, Bei Liu, Serafima Guseva, Hashim M. Al‐Hashimi

This study measures sequence-dependent A-T Hoogsteen dynamics in DNA using NMR, revealing distinct conformational specificity and sequence dependence.

Biochemistry · Feb 21, 2025Peer-reviewedBiochemistry