Yu Young Jeong

This study identifies dysregulated autophagosome-mitochondria contacts in tauopathy, showing that restoring these contacts improves autophagy and reduces tau pathology.

This study shows that deleting Wasf1 in P301S tau mice reduces tau hyperphosphorylation, improves cognition, and restores microglial function.

This study shows that boosting mitochondrial bioenergetics enhances autophagy and clears pathological tau in tauopathy neurons, suggesting a new therapeutic approach for Alzheimer's and other tauopathies.