Dysregulation of a novel autophagosome-mitochondria contact contributes to autophagy dysfunction and neurodegeneration in tauopathy
Nuo Jia, Hongyuan Guan, Yantao Zuo…·Qian Cai
This study identifies dysregulated autophagosome-mitochondria contacts in tauopathy, showing that restoring these contacts improves autophagy and reduces tau pathology.