Alexander W. Kusnecov

This study identifies dysregulated autophagosome-mitochondria contacts in tauopathy, showing that restoring these contacts improves autophagy and reduces tau pathology.

This study shows that neuronal DAMPs activate astrocytic RIPK3 signaling, leading to neuroinflammation and dopaminergic cell death in Parkinson's disease.

This study shows that boosting mitochondrial bioenergetics enhances autophagy and clears pathological tau in tauopathy neurons, suggesting a new therapeutic approach for Alzheimer's and other tauopathies.