Author

David Buchta

Masaryk UniversityORCID 0000-0001-6787-6355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

David Zapletal· 1 shared Diego F. JosephiD· 1 shared Ján Petrovský· 1 shared Josef PasulkaiD· 1 shared Karel KubíčekiD· 1 shared N. V. NoskovaiD· 1 shared Petr SvobodaiD· 1 shared Radek Malı́kiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

David Zapletal

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 20, 2026

A negatively charged unstructured loop autoinhibits mammalian Dicer and supports fidelity of miRNA biogenesis.

Diego F. Joseph, N. V. Noskova, Radek Malı́k…·Richard Štefl

The paper shows that a negatively charged intrinsically disordered region (IDR) in Dicer autoinhibits the enzyme and ensures fidelity of miRNA biogenesis.

DOI 10.64898/2026.02.19.706781

humanexperimental assay

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