Author
Central European Institute of Technology – Masaryk UniversityORCID 0000-0002-8990-4481Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Diego F. Joseph, N. V. Noskova, Radek Malı́k…·Richard Štefl
The paper shows that a negatively charged intrinsically disordered region (IDR) in Dicer autoinhibits the enzyme and ensures fidelity of miRNA biogenesis.
Marek Šebesta, Karel Skubnik, William Morton…·Richard Štefl
This study identifies two mechanisms by which RECQ5 modulates RNA polymerase II transcription: attenuating elongation via the brake helix and forming a condensate scaffold matrix.
Durga Jha, Gabriela Dovrtělová, Petr Telenský…·Zdeněk Spáčil
The paper analyzes ganglioside profiles in rat brains and fluids across age and regions, finding age-related shifts in a-series to b-series ratios and region-specific changes.
David Zapletal, Eliška Táborská, Josef Pasulka…·Petr Svoboda
This study identifies the DExD/H helicase domain of Dicer as critical for accurate miRNA biogenesis, showing its role in substrate recognition, cleavage, and strand selection in mammals.
Zhong Han, Olga Jasnovidova, Nouhou Haidara…·Odil Porrúa
The paper identifies a CTD-mimic motif in Sen1 that interacts with Nrd1's CTD-interacting domain to facilitate ncRNA termination in yeast.