Author

Kai Song

University of California, Los AngelesORCID 0000-0001-6792-7159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

John K. LeeiD· 2 shared Thomas G. GraeberiD· 2 shared Vipul BhatiaiD· 2 shared Arthur J. Y. HuangiD· 1 shared Brian P. HanrattyiD· 1 shared Chenchen Xu· 1 shared Cherry Y N Wong· 1 shared Chia‐Chun CheniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

John K. LeeORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 8, 2026

FFPERescuer: deep unsupervised domain adaptation for the reconstruction of gene expression profiles derived from formalin-fixed paraffin-embedded samples

Lingli He, Kai Song, Ying Li…·Xin Wang

FFPERescuer uses deep learning to improve gene expression reconstruction from degraded FFPE samples, achieving high accuracy and enhancing cancer subtyping.

DOI 10.64898/2026.09.02.748790

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintFeb 12, 2025

Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer

Shan Li, Kai Song, Huiyun Sun…·John K. Lee

This study reprograms AR-active prostate cancer to NEPC using ASCL1 and NeuroD1, revealing their role in silencing AR and altering chromatin structure.

4 citations

humanChIP-seq

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Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedNov 26, 2024

PGC-1a drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity

Grigor Varuzhanyan, Chia‐Chun Chen, Jack Freeland…·Owen N. Witte

21 citations

humanbulk RNA-seq

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