John W. Calvert

This study develops an LRH-1 agonist that improves insulin sensitivity and reduces liver fat in obese mice, revealing peroxisomal lipid metabolism as a key pathway.

This study investigates the role of neutrophil-specific STING in myocardial ischemia/reperfusion injury, finding that its deletion worsens cardiac function and alters immune cell responses.

This study identifies CBX7 as a repressor of cardiomyocyte proliferation by modulating the TARDBP/Rbm38 axis during the perinatal period.