PhysiologybioRxivPreprint
An LRH-1 agonist reverses hepatic metabolic dysfunction in obesity
Suzanne G Mays, André R Cuevas, Racheal M Spurlin…·John W Calvert
This study develops an LRH-1 agonist that improves insulin sensitivity and reduces liver fat in obese mice, revealing peroxisomal lipid metabolism as a key pathway.
DOI 10.64898/2026.10.28.761933