BiochemistryBiochemistryPeer-reviewed
Improved Protein Semi-Synthesis Enables Biophysical Studies of Thioamide Destabilization of β-Sheet Interactions
Evan S. K. Yanagawa, Kristen E. Fiore, Denver Y. Francis…·E. James Petersson
This paper develops a method to synthesize thioamide-containing proteins and shows they destabilize β-sheet structures in GB1 and α-synuclein fibrils.
DOI 10.1021/acs.biochem.6c00371