Maurício Rocha-Martins

The paper shows that neurogenic progenitors in zebrafish retinas can undergo self-renewal to compensate for apoptosis, ensuring proper development despite cell loss.

This study shows that overexpressing Pou4f2 in late retinal progenitors generates RGC-like neurons with axonal projections to brain regions.

The paper uses live imaging to show that retinal progenitors make both deterministic and probabilistic fate decisions, with stochasticity increasing under developmental stress.

The paper shows bidirectional neuronal migration prevents spatial competition during retinal morphogenesis in zebrafish, human tissue, and organoids.

The paper shows that Notch regulates asymmetric neurogenic commitment in zebrafish retinal progenitors through Sara-positive endosomes, revealing a new mechanism for progenitor differentiation.

This paper shows that overexpressing Klf4 in retinal progenitor cells can reprogram them to generate retinal ganglion cells in vivo, with iRGCs surviving for up to 30 days.

This paper demonstrates how deep learning-based image restoration extends fluorescence microscopy's capabilities by improving resolution, reducing photon exposure, and increasing frame rates.