Author

Pedro L. Santos-França

Universidade Federal do Rio de JaneiroORCID 0000-0001-7871-8125Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Beatriz Cardoso de ToledoiD· 2 shared Mariana S. SilveiraiD· 2 shared Maurício Rocha-MartinsiD· 2 shared Rafael LindeniD· 2 shared Rodrigo A. P. MartinsiD· 2 shared Viviane M. Oliveira-ValençaiD· 2 shared Alejandra BoscoiD· 1 shared Allie Cui· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersNeuroscience

Beatriz Cardoso de ToledoORCID

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3 papers

Recent·Most cited

NeuroscienceDevelopmentPeer-reviewedFeb 13, 2025

Pou4f2/Brn3b Overexpression Promotes The Genesis Of Retinal Ganglion Cell-Like Projection Neurons From Late Progenitors

Viviane M. Oliveira-Valença, Jacqueline M. Roberts, Vitória Melo Fernandes-Cerqueira…·Mariana S. Silveira

This study shows that overexpressing Pou4f2 in late retinal progenitors generates RGC-like neurons with axonal projections to brain regions.

2 citations

mousespatial transcriptomics

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedDec 20, 2022

Ikaros family proteins regulate developmental windows in the mouse retina through convergent and divergent transcriptional programs

Awais Javed, Pedro L. Santos-França, Pierre A. Mattar…·Michel Cayouette

This study shows Ikzf1 and Ikzf4 regulate distinct cell fates in the mouse retina through different cis-regulatory elements and temporal expression patterns.

38 citations

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedJan 1, 2019

De novo genesis of retinal ganglion cells by targeted expression of KLF4 in vivo

Maurício Rocha-Martins, Beatriz Cardoso de Toledo, Pedro L. Santos-França…·Mariana S. Silveira

This paper shows that overexpressing Klf4 in retinal progenitor cells can reprogram them to generate retinal ganglion cells in vivo, with iRGCs surviving for up to 30 days.

22 citations

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