Beatriz Cardoso de Toledo

This study shows that overexpressing Pou4f2 in late retinal progenitors generates RGC-like neurons with axonal projections to brain regions.

The paper characterizes alternative splicing during mammalian brain development, revealing extensive isoform diversity and its impact on protein conformational changes.

The paper profiles miRNAs in mouse cortical progenitors and neurons, identifying miR-486-5p as a novel regulator of neurogenesis.

This paper shows that overexpressing Klf4 in retinal progenitor cells can reprogram them to generate retinal ganglion cells in vivo, with iRGCs surviving for up to 30 days.