Author

Dinesh Rakheja

Children's Medical CenterORCID 0000-0001-6888-7902Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Dinesh Rakheja1 paper

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alana L. ChristieiD· 1 shared Aleksandra W. NielseniD· 1 shared Anna K. LeeiD· 1 shared Asha Acharya· 1 shared Averi Perny· 1 shared Barbara BreznikiD· 1 shared Benjamin T. JonesiD· 1 shared Bret M. EversiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBioinformatics

Alana L. ChristieORCID

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Author profile →

3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 1, 2026

A Visually Interpretable Histopathology-Based Immune Model Predicts T-effector Biology and Response to Immune checkpoint inhibition in Clear Cell Renal Cell Carcinoma Clinical Trial and Contemporary Real-World Datasets

Averi Perny, Vipul Nataraj Jarmale, Jay Jasti…·Satwik Rajaram

The paper develops a deep learning model from H&E images to predict T-effector biology and ICI response in ccRCC, showing strong correlation with RNA-based scores and clinical outcomes.

DOI 10.64898/2026.06.21.733614

humanspatial transcriptomics

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Cancer BiologyActa Neuropathologica CommunicationsPeer-reviewedJul 28, 2025

Melanoma antigens in pediatric medulloblastoma contribute to tumor heterogeneity and species-specificity of group 3 tumors

Rebecca R. J. Collins, Rebecca R. Florke Gee, Sima Tozandehjani…·Klementina Fon Tacer

This study identifies MAGE antigens as markers of tumor heterogeneity and species-specificity in group 3 medulloblastoma, showing their role in cell survival and potential as therapeutic targets.

3 citations

humanbulk RNA-seq

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Molecular BiologyGenes & DevelopmentPeer-reviewedJul 1, 2023

Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals

Benjamin T. Jones, Jaeil Han, He Zhang…·Joshua T. Mendell

This study shows that target-directed miRNA degradation (TDMD) regulates miRNA expression and embryonic growth in mammals by deleting Zswim8 and analyzing miRNA changes.

38 citations

mousebulk RNA-seq

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