Author

Michelle Ka Yan Wu

Memorial Sloan Kettering Cancer CenterORCID 0000-0001-6889-8345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:whole-genome sequencing· 3 Research Focus:clustering· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:deconvolution· 1 Approach:deep learning· 1

Frequent Co-Authors

Andrew McPhersoniD· 2 shared Britta WeigeltiD· 2 shared Carol A AghajanianiD· 2 shared Claire Frances FriedmaniD· 2 shared Dmitriy ZamariniD· 2 shared Duaa Hassan Al-RawiiD· 2 shared Eliyahu Havasov· 2 shared Emily AliiD· 2 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Andrew McPhersonORCID

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3 papers

Recent·Most cited

Cancer BiologyNaturePeer-reviewedOct 1, 2025

Tracking clonal evolution of drug resistance in ovarian cancer patients by exploiting structural variants in cfDNA

Marc J. Williams, Ignacio Vázquez-Garćıa, Grittney K. Tam…·Sohrab P. Shah

This study tracks clonal evolution of drug resistance in ovarian cancer using structural variants in cfDNA, finding polyclonal resistance with dominant high-fitness clones and genomic features linked to drug resistance.

33 citationstop 1%

humanwhole-genome sequencing

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Cancer BiologyNaturePeer-reviewedJul 16, 2025

Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer

Andrew McPherson, Ignacio Vázquez-Garćıa, Matthew A. Myers…·Sohrab P. Shah

This study shows that ongoing whole-genome doubling in ovarian cancer promotes cell diversity and immune dysregulation through chromosomal instability and quiescent states.

66 citationstop 1%

humanscRNA-seq

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GenomicsGenome ResearchPeer-reviewedMay 1, 2019

Efficient long single molecule sequencing for cost effective and accurate sequencing, haplotyping, and de novo assembly

Ou Wang, Robert G. Chin, Xiaofang Cheng…·Brock A. Peters

This paper introduces stLFR, a low-cost method for long DNA sequencing that enables accurate variant calling, haplotyping, and de novo assembly.

232 citations

humanwhole-genome sequencing

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