Jessica M. A. Blair

The paper shows that a single HTH domain from MarA can bind DNA and activate transcription when properly dimerized, revealing structural insights for synthetic biology applications.

The paper identifies a seventh RND efflux pump, EefABC, in E. coli phylogroups associated with infection, showing high conservation and distinct structural features compared to known systems.

This study shows that MGB-BP-3, a minor groove binder, is more effective against Gram-negative bacteria like E. coli under nutrient-limited conditions than in rich media, with in vivo efficacy in a Galleria mellonella model.

This study identifies the N-terminal helix of MarA as critical for DNA binding, showing its role in recognizing marboxes and suggesting it as a target for antibiotic resistance inhibitors.

The paper uses dynamic Boolean modeling to show how ATP variability affects efflux pump gene expression in bacteria, revealing energy-dependent heterogeneity in antimicrobial resistance.