Author

Yupeng Chen

University of ConnecticutORCID 0000-0001-6940-6277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Anne YauiD· 2 shared Ian SandsiD· 2 shared Maxwell Landolina· 2 shared Wuxia ZhangiD· 2 shared Brandon Williams· 1 shared Derek Duflo· 1 shared Elham AhmadiiD· 1 shared Hongchuan YuiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

Anne YauORCID

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3 papers

Recent·Most cited

BioengineeringJournal of Controlled ReleasePeer-reviewedAug 26, 2025

Computation-aided Design of Rod-Shaped Janus Base Nanopieces for Improved Tissue Penetration and Therapeutics Delivery

Jinhyung Lee, Wuxia Zhang, Thanh Danh Nguyen…·Yupeng Chen

This study develops rod-shaped Janus base nanopieces for improved tissue penetration and therapeutics delivery, showing better efficacy than spherical lipid nanoparticles in ovarian cancer models.

8 citations

deep learningstatistical model

𝕏 PostBluesky

Bioengineeringnpj MicrogravityPeer-reviewedJul 2, 2025

In-Space Fabrication of Janus Base Nano-Matrix for Improved Assembly and Bioactivities

Anne Yau, Maxwell Landolina, Mari Anne Snow…·Yupeng Chen

The paper demonstrates the fabrication of DNA-inspired Janus base nanomaterials in space, showing their potential for in-space manufacturing.

5 citations

experimental assay

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BioengineeringbioRxivPreprintOct 5, 2024

Injectable Janus Base Nanomatrix (JBNm) in Maintaining Long-Term Homeostasis of Regenerated Cartilage for Tissue Chip Applications

Anne Yau, Ian Sands, Wuxia Zhang, Yupeng Chen

This paper develops an injectable Janus base nanomatrix (JBNm) to maintain long-term cartilage homeostasis in tissue chips, supporting chondrogenesis while inhibiting fibrosis, hypertrophy, and angiogenesis.

1 citation

organoid / primary cultureexperimental assay

𝕏 PostBluesky