Perry G. Ridge

The paper shows that a synonymous variant in PILRA decreases mRNA and protein levels by disrupting a ramp sequence, providing a biological mechanism for its association with Alzheimer's disease.

The paper develops a Pacific ancestry pangenome reference to improve genetic analysis for an underserved population, showing it reduces variant call errors and captures novel sequence.

This paper presents a high-quality genome assembly and associated data for the giant trevally, providing resources for ecological and comparative genomics studies.

The paper generates a high-quality genome assembly for the roundjaw bonefish and analyzes population genetic connectivity in the Western Indian Ocean.

The paper identifies dark and camouflaged gene regions in the human genome, shows how long-read sequencing reduces their prevalence, and applies an algorithm to uncover disease-relevant variants in Alzheimer's Disease Sequencing Project data.

The paper evaluates gene-gene interactions between CLU and MS4A4E variants in Alzheimer’s disease using a large dataset, finding a significant interaction and estimating its population attributable fraction.