Christophe M. Lamy

Whole human organ clearing and multimodal mapping

This paper introduces mCleLight, a method for clearing, labeling, and imaging whole human tissues, enabling multiscale analysis of organ architecture.

CleLight: A scalable 3D histology pipeline for mappingneurodegenerative and psychiatric pathology in archivalhuman brains

CleLight improves transparency and reduces autofluorescence in human brain tissue, enabling detailed imaging of pathological features in archival samples.

Quantification of Human DNA from Century-Old Archived FFPE Samples for Retrospective Genomic Studies

This paper quantifies DNA from century-old FFPE samples and shows that storage time is less impactful on DNA quality than initial fixation time, requiring NGS for analysis.

Efficient image analysis for large-scale next generation histopathology using pAPRica

The paper introduces pAPRica, a framework for efficient analysis of large-scale histopathology images, achieving significant speedup and data reduction.

Oxytocin Acts on Astrocytes in the Central Amygdala to Promote a Positive Emotional State

This study shows that oxytocin acts on astrocytes in the central amygdala to promote a positive emotional state, challenging the notion that oxytocin only affects neurons.