Author
VIB-KU Leuven Center for Brain & Disease ResearchORCID 0000-0002-3816-4583Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jérôme Wahis, Cansu Akkaya, Andre M. Kirunda, Aline Mak, Karen D. Zeise, Jens Verhaert, Hayk A. Gasparyan, Sargis A. Hovhannisyan, Matthew G. Holt
This study investigates the role of astrocyte 1A-adrenoreceptors in noradrenergic signaling in mouse visual cortex, finding they regulate calcium transients and synaptic plasticity.
Glia · Jul 12, 2024Peer-reviewedNeuroscience
Disha Shah, Willy Gsell, Jérôme Wahis, Emma Susanne Luckett, Tarik Jamoulle, Ben Vermaercke, Pranav Preman, Daan Moechars, Véronique Hendrickx, Tom Jaspers, Katleen Craessaerts, Katrien Horré, Leen Wolfs, Mark W. E. J. Fiers, Matthew G. Holt, , Bart De Strooper
The paper shows that astrocyte calcium dysfunction leads to early network hyperactivity in Alzheimer's Disease, which can be reversed by restoring calcium signaling.
Cell Reports · Aug 1, 2022Peer-reviewedNeuroscience
Jérôme Wahis, Angel Baudon, Ferdinand Althammer, Damien Kerspern, Stéphanie Goyon, Daisuke Hagiwara, Arthur Lefèvre, Lara Barteczko, Benjamin Boury‐Jamot, Benjamin Bellanger, Marios Abatis, Miriam Da Silva Gouveia, Diego Benusiglio, Marina Eliava, Andrei V. Rozov, , Alexandre Charlet
This study shows that oxytocin acts on astrocytes in the central amygdala to promote a positive emotional state, challenging the notion that oxytocin only affects neurons.
Nature Neuroscience · Feb 15, 2021Peer-reviewedNeuroscience
Mykhailo Y. Batiuk, Araks Martirosyan, Jérôme Wahis, Filip de Vin, Catherine Marneffe, Carola Kusserow, Jordan Koeppen, João Filipe Viana, João Filipe Oliveira, Thierry Voet, Chris Paul Ponting, T. Grant Belgard, Matthew G. Holt
The paper identifies molecularly distinct astrocyte subpopulations in the adult mouse brain and shows their spatial distribution has functional implications.
Nature Communications · Mar 5, 2020Peer-reviewedNeuroscience