Author

Pascal Senn

University of GenevaORCID 0000-0002-4619-3341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Francis RoussetiD· 3 shared Stéphanie Sgroi· 3 shared Dimitrios DaskalouiD· 2 shared Lucie OberhauseriD· 2 shared Cecilia de HeusiD· 1 shared Céline BrockmanniD· 1 shared Christophe M. LamyiD· 1 shared Cindy G. J. CleypooliD· 1 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersNeuroscience

Francis RoussetORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Deciphering auditory neuroprogenitor stemness for large-scale neuronal screening

Francis Rousset, Lorenzo Pepe, Moein Sarhadi, Sylvain Lemeille, Stéphanie Sgroi, Lucie Oberhauser, Dimitrios Daskalou, Sten Ilmjärv, Simon Braun, Pascal Senn

The paper characterizes the molecular and metabolic changes in auditory neuroprogenitors induced by CHIR-DS treatment and demonstrates their utility in neuronal screening.

bioRxiv · Oct 13, 2026 · PreprintNeuroscience

LGR5 and SOX2 expressing progenitor cells in the adult and aged human and mouse inner ear have the potential to produce Myosin 7A positive cells in vitro

Georgina E. Fenton, Tobias Pieper, Cindy G. J. Cleypool, Stéphanie Sgroi, Francis Rousset, Cecilia de Heus, Nalan Liv, Hans G. X. M. Thomeer, Pascal Senn, Robert Jan Stokroos, Louise V. Straatman, Natalia Smith‐Cortinez

The paper shows adult human and mouse inner ear progenitor cells can generate Myosin 7A positive cells in vitro, suggesting regenerative potential for hearing loss.

bioRxiv · Sep 24, 2026 · PreprintNeuroscience

Whole human organ clearing and multimodal mapping

Héloïse Policet-Bétend, Tomás Jordá-Siquier, Géraldine Cuenu, Maeva Badre, Sami Schranz, Julien Da Costa, Céline Brockmann, Pascal Senn, Daniel Huber, Christophe M. Lamy

This paper introduces mCleLight, a method for clearing, labeling, and imaging whole human tissues, enabling multiscale analysis of organ architecture.

bioRxiv · Jul 24, 2026 · PreprintCell Biology

Introducing a translationally relevant mouse model of radiosurgery-induced unilateral hearing loss

Dimitrios Daskalou, Francis Rousset, Stéphanie Sgroi, Lucie Oberhauser, Jean‐Philippe Thiran, Constantin Tuleasca, Ileana Jelescu, Marc Levivier, Pascal Senn

This paper introduces a mouse model of radiosurgery-induced unilateral hearing loss and shows dose-dependent hearing loss and cochlear damage.

Frontiers in Neuroscience · May 7, 2026Peer-reviewedNeuroscience