Alexandre Charlet

The paper shows that acetylcholine activates astrocytic JAK2-STAT3 signaling in male mice, which is necessary for context-appropriate approach behavior toward estrus females.

This study identifies a circuit in the medial prefrontal cortex where oxytocin modulates interneurons to promote social behavior in female rats, even under physiological stress.

This study shows that OXTR signaling in lateral septum astrocytes regulates social fear in a sex-dependent manner in mice.

The paper shows that oxytocin-induced astrocyte process retraction in the amygdala modulates freezing behavior during stress by enhancing neuronal sensitivity to potassium.

This study investigates changes in the oxytocinergic circuit in the central amygdala of rats with chronic heart failure, finding impaired OT release and receptor function.

This study examines the oxytocin system and OTR-expressing astrocytes in a mouse model of PWS, finding reduced oxytocin cells and OTR-expressing astrocytes in specific brain regions with sex-specific differences.

The paper investigates changes in the PVN-to-CA2 oxytocin pathway in heart failure rats, finding altered oxytocinergic innervation and reduced OTR-expressing astrocytes.

The paper identifies a novel analgesic pathway involving parvocellular oxytocin neurons projecting to the vlPAG, which suppresses spinal cord sensory neuron activity and alleviates pain.

This study shows that oxytocin acts on astrocytes in the central amygdala to promote a positive emotional state, challenging the notion that oxytocin only affects neurons.

This study shows that endogenous oxytocin release in the periaqueductal gray suppresses spinal cord pain perception neurons, reducing mechanical pain but not heat pain in inflammation models.