Author

Štěpán Coufal

Czech Academy of SciencesORCID 0000-0001-6950-1813Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Anna HerrmannováiD· 1 shared Anna M. Smirnova· 1 shared Christine VogeliD· 1 shared Denisa PetráčkováiD· 1 shared Dominik FilippiD· 1 shared Dušan HrčkulákiD· 1 shared Jakub OnhajzeriD· 1 shared Jan KubovčiakiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Anna HerrmannováORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivJul 11, 2024

The fate of secretory cells during intestinal homeostasis, regeneration, and tumor formation is regulated by Tcf4

Lucie Janečková, Monika Šťastná, Dušan Hrčkulák…·Vladimír Kořínek

This study investigates the role of Tcf4 in intestinal epithelial regeneration and tumorigenesis using mouse models and RNA sequencing, finding that Tcf4 loss shifts cell lineage from Paneth to goblet cells and affects tumor cell phenotypes.

DOI 10.1186/s13287-025-04280-y

mousebulk RNA-seq

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Molecular BiologyCell ReportsPeer-reviewedMar 19, 2024

Stem-loop induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control

Anna M. Smirnova, Vladislava Hronová, Mahabub Pasha Mohammad…·Leoš Shivaya Valášek

The paper identifies a stem-loop and modified adenines in the uORF2/ATF4 overlap that regulate ATF4 translation under stress, revealing a more complex mechanism than previously thought.

25 citations

humanproteomics

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