Cell BiologybioRxivPreprint
Securin and cyclin B1-CDK1, but not SGO2, regulate separase activity during meiosis I in mouse oocytes
Benjamin Wetherall, David M. Bulmer, Alexandra Sarginson…·Suzanne Madgwick
This study shows that securin and cyclin B1-CDK1, but not SGO2, independently inhibit separase during meiosis I in mouse oocytes, and their combined loss leads to premature separase activation.
DOI 10.1101/2025.01.06.631516