Samantha Donsante

This paper develops a humanized ossicle model to track CAR-T cell dynamics and AML progression in real-time, enabling preclinical assessment of immunotherapies.

The paper uses time-lapse imaging to analyze lineage topology and replication kinetics in human BMSC colonies, revealing synchronized cell cycles and regulatory factors linking non-dividing cells with proliferating cells.

This study investigates how RANKL inhibition affects bone formation in a mouse model of fibrous dysplasia, finding that bone formation is restricted to specific surfaces rather than occurring diffusely.

The paper quantifies hereditary epigenetic regulation of cell-cycle exit in human bone marrow stromal cells using a novel entropy metric applied to clonal colony data.

This study shows that bone pain in Fibrous dysplasia is intrinsic and not caused by abnormal sensory nerve sprouting or neuroma formation.