Biagio Palmisano

Lineage topology, replication kinetics and cell cycle synchronization reveal regulated growth dynamics in human bone marrow stromal cell colonies

The paper uses time-lapse imaging to analyze lineage topology and replication kinetics in human BMSC colonies, revealing synchronized cell cycles and regulatory factors linking non-dividing cells with proliferating cells.

Exploring the mechanism and pattern of bone formation during RANKL inhibition in a mouse model of fibrous dysplasia

This study investigates how RANKL inhibition affects bone formation in a mouse model of fibrous dysplasia, finding that bone formation is restricted to specific surfaces rather than occurring diffusely.

Effects of anti-RANKL, Zoledronate or combination therapy in a mouse model of Fibrous Dysplasia: a preclinical study

This study evaluates the combination of zoledronate and anti-RANKL therapy in a mouse model of fibrous dysplasia, showing delayed disease rebound and improved bone density.

3D bone printing via primed differentiation of stem cells with ultrasound (3DBonUS)

This paper introduces 3DBonUS, a 3D bone printing method using ultrasound and microfluidic bioprinting to direct stem cell differentiation, showing increased osteogenic markers and mineralization.

Inheritance entropy quantifies epigenetic regulation of cell-cycle exit in human bone marrow stromal cells

The paper quantifies hereditary epigenetic regulation of cell-cycle exit in human bone marrow stromal cells using a novel entropy metric applied to clonal colony data.

Pde5a Deficiency Prevents Diet-Induced Obesity via Adipose cAMP-PKA Activation Enhancing Fat Browning

This study shows that Pde5a deficiency prevents diet-induced obesity by enhancing adipose cAMP-PKA activation, leading to fat browning and improved metabolic outcomes.

Engineering a microfluidic-assisted 3D bioprinting approach for the hierarchical control deposition and compartmentalisation of graded bioinks

This paper introduces a microfluidic-assisted 3D bioprinting system that enables precise control over cell compartmentalization and material composition for creating interconnected, functional tissue constructs.

Aqueous two-phase bioinks for discrete packing and compartmentalisation of 3D bioprinted cells

This paper develops ATPS bioinks for 3D bioprinting that enable precise cellular compartmentalization and tissue regeneration.

Bone pain in Fibrous dysplasia does not rely on aberrant sensory nerve sprouting or neuroma formation

This study shows that bone pain in Fibrous dysplasia is intrinsic and not caused by abnormal sensory nerve sprouting or neuroma formation.