Author

Laki Buluwela

Imperial College LondonORCID 0000-0001-6973-334XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

Simak AliiD· 2 shared Andrew C.B. CatoiD· 1 shared Barbara BellettiiD· 1 shared Bente A. SomseniD· 1 shared Christian OttmanniD· 1 shared Christine BlattneriD· 1 shared Christoph W. GrathwoliD· 1 shared Damir VarešlijaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Simak AliORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 28, 2025

Distinct 2-phenyl-imidazo pyridine derivatives drive ER degradation and selectively impair proliferation of ER+ breast cancer cells via the aryl hydrocarbon receptor

Katrin Koellisch, Christine Blattner, Stefano Motta…·Andrew C.B. Cato

The paper identifies X15695 as an AHR ligand that promotes ER degradation and inhibits ER+ breast cancer cell proliferation more effectively than fulvestrant.

1 citation

humanexperimental assay

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Cancer BiologybioRxivPreprintApr 25, 2024

Estrogen Receptor alpha/14-3-3 molecular glues as alternative treatment strategy for endocrine resistant breast cancer

Emira J. Visser, Maria Donaldson Collier, Joseph C. Siefert…·Luc Brunsveld

This study investigates molecular glues targeting the ER/14-3-3 PPI to overcome endocrine resistance in breast cancer, showing suppression of ER activity and cell proliferation.

6 citations

humanproteomics

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