Jianping Lin

This paper introduces AiPP, an AI-based platform for predicting ligandable sites in the human proteome, and demonstrates its application in discovering covalent inhibitors for PTPN6.

This study identifies macrophage-driven NK cell infiltration during tumor regression and subsequent exclusion during residual disease as key factors in therapy resistance, highlighting macrophage-NK cell crosstalk as a therapeutic target.

This study uses mt-QSAR models to predict multitarget inhibitors for HIV/HCV co-infection, identifying 18 potential compounds with confirmed interactions.