Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50
Eyal Paz, Sahil Jain, Irit Gottfried, Orna Staretz‐Chacham, Muhammad Mahmoud Mahajnah, Pritha Bagchi, Nicholas T. Seyfried, Uri Ashery, Abdussalam Azem
This study investigates the effects of TIMM50 deficiency in human fibroblasts and mouse neurons, finding reduced mitochondrial function and altered potassium channel levels linked to neurological symptoms.
bioRxiv · May 20, 2024Biochemistry