MicrobiologybioRxivPreprint
Viral SSB-bound ssDNA activates the bacterial anti-phage defense system DARNA
Rugile Puteikiene, Christopher N. Vassallo, Arūnas Šilanskas…·Giedrius Sasnauskas
This study shows that viral SSB-bound ssDNA activates the bacterial anti-phage defense system DARNA by recognizing a signal promoted by viral proteins, enabling broad virus detection without auto-immunity.