Molecular BiologybioRxivPreprint
The novel coronary artery disease risk factor ADAMTS-7 modulates atherosclerotic plaque formation by degradation of TIMP-1
M. Amin Sharifi, Michael Wierer, Tan An Dang…·Thorsten Kessler
This study identifies ADAMTS-7 as a risk factor for atherosclerosis by degrading TIMP-1, reducing its inhibition of MMP-9 and promoting collagen degradation.