Author

Surajit Chakraborty

Cleveland ClinicORCID 0000-0001-7004-2909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

Michaela Ulrike GackiD· 2 shared Anna A. TumanovaiD· 1 shared Caleb M. StrattoniD· 1 shared Cindy Chiang· 1 shared Deion Cheng· 1 shared Donna A. MacDuffiD· 1 shared Guanqun LiuiD· 1 shared Jonathan N. PrunedaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Michaela Ulrike GackORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ImmunologymBioPeer-reviewedOct 22, 2026

HOIL1 mediates MDA5 activation through ubiquitination of LGP2

Deion Cheng, Junji Zhu, W. A. Gayan Chathuranga…·Donna A. MacDuff

This study shows HOIL1 ubiquitinates LGP2 to activate MDA5 and induce IFN responses, highlighting a mechanism distinct from RIG-I sensing.

3 citations

humanproteomics

MicrobiologybioRxivPreprintJul 28, 2025

Inhibition of coronaviral exonuclease activity by TRIM-mediated SUMOylation

Kannan Balakrishnan, Surajit Chakraborty, Cindy Chiang…·Michaela Ulrike Gack

The paper identifies TRIM32 as an antiviral protein that inhibits SARS-CoV-2 replication by SUMOylating NSP14, thereby blocking its exonuclease activity.

2 citations

humanexperimental assay