Cell BiologybioRxivPreprint
The unfolded protein response turns from pro-survival to pro-death to cap the extent of endoplasmic reticulum expansion
Milena Vitale, Andrea Orsi, Anush Bakunts…·Eelco van Anken
The paper shows the UPR transitions from pro-survival to pro-death when ER expansion is excessive, using HeLa cells and genetic manipulations.
DOI 10.1101/134726