Kira Céline Koonce

This study shows that soluble mucin glycans delay Escherichia coli phage T4 infection initiation but enhance virion stability and persistence in the gut.

The paper engineers anti-quorum sensing phages that degrade quorum-sensing molecules, reduce virulence, and improve survival in infected larvae, demonstrating their potential to enhance phage therapy.

This study shows that phage lysates retain bioactive quorum sensing signals like PQS, which can influence bacterial behavior, independent of phage infection.